Ebola


Ebola hemorrahagic fever is a 20 year old virus that, with a mortality
rate of 50% to 90%, is one of the world\'s deadliest viruses. Its causative
organism is called Ebola virus. Ebola virus is a member of filoviridae, a
family of negative-strained RNA viruses. The filoviridae family consists of
five known members, Marburg, Ebola Zaire, Ebola Sudan, Ebola Reston, and Ebola
Tai.
Ebola virus is spread in a number of ways. An outbreak starts when an
infected animal or insect, called a vector, transmits the virus to a human.
Scientists know that monkeys are both a vector and victim of Ebola, but other
vectors are unknown. The natural reservoir for the virus, or organism that is
immune to it and carries it is also unknown. A search for the reservoir will
take a long time because there are so many possibilities, since Africa is in the
tropics. Another way that humans can get Ebola is by eating an infected animal
or drinking the milk of an infected animal.
Ebola is spread from human to human by contact with infected blood,
infected body fluids, or through sexual contact. Even after a person recovers
completely from Ebola, it may stay in the semen for up to seven weeks. In the
African outbreaks it has also been transmitted by the reuse of needles because
the health care systems are so under financed. Ebola wasn\'t thought to be an
airborne virus, but recent studies by the US Army Medical Research Institute of
Infectious Diseases and the CDC found that monkeys showed Ebola like symptoms
after being exposed to aerosolized Ebola. The studies also found that the virus
is many times present in the respiratory systems of Ebola victims. Although the
1989 outbreak in Reston, Virginia wasn\'t harmful to humans, it was found that
droplet and vomit transmission played a major role in spreading the disease
through the quarantine facility.
The onset of the Ebola virus is very quick. The incubation period
ranges anywhere from two days to twenty-one days. After signs of the virus
appear, the victim can die within days, or at the most, a week. There are a
few stages after being infected with the virus. The symptoms of the first stage
include headaches, fever, muscle pain, fatigue, chills, and loss of appetite.
The second stage consists of vomiting, diarrhea, abdominal pain, sore throat,
and chest pain. The last stages are very ugly. They consist of severe clotting
and hemorrhaging. The clots form throughout the body and shut of blood to many
organs, especially the brain, liver, and spleen. These organs that don\'t
receive blood begin to decay. Blood leaks into tissues, fills internal cavities,
and stops clotting. Blood leaks through the skin and all other openings. The
skin becomes very easily ripped and the victim can bleed profusely just by being
touched. Then the body\'s connective tissues lose their stretchiness and become
very spongy. Hemorrhages and blood clots in the brain cause the person\'s face
to become expressionless and frozen. The Ebola virus spreads to all fluids in
the body and the victim eventually dies from blood loss and shock. When the
victim dies all that is left is a decayed body filled with virus particles.
Ebola virus is diagnosed in only one way. It is diagnosed in
specialized laboratory tests on blood specimens. These tests look for Ebola
antigens, antibodies, or the isolated virus in the specimens. Since the virus
is so deadly, these diagnostic tests are an extreme biohazard and are performed
only with extreme caution.
The Ebola virus is the world\'s third deadliest infectious disease,
behind HIV, and rabies, which has a vaccine. The only treatment that can be
given to Ebola victims is support. They are usually very dehydrated and need
management of fluid and electrolyte balance. Victims may sometimes require IV
feeds to replace liquids. Before shock occurs it may be helpful to replace
plasma albumin. There is currently no cure or vaccine for the Ebola virus.,
although it is recorded that someone in the United Kingdom was infected with
Ebola Zaire and was injected with the plasma of a recovered Ebola Zaire victim
and recovered fully. The opposite was also shown when recovered Ebola Reston
monkeys were infected with Ebola Zaire and died faster than monkeys infected
with just the Ebola Zaire strain. Therefore, it is thought that plasma
injections only work on common strain victims.
The first occurrence of the Ebola virus was discovered in July of 1979
near the Ebola River in Northern Zaire after a worker in a cotton factory in
Nzara, Sudan became very ill. Later that year a similar virus spread through
more than 50